Human Dendritic Cells-Peripheral Blood: HDC-PB

Human Dendritic Cells from Peripheral Blood (HDC-PB) arise from a distinct hematopoietic lineage and help regulate the immune system.  They mount adaptive immune responses to foreign antigens, “prime” T cells through antigen presentation and can induce tolerance to self-antigens.  Academic & industrial research is driving toward potential therapeutic benefits of modulating DCs for vaccines and suppressive therapies against pathogens, tumors and autoimmune diseases.  HDC constitutively express CD11c, a type I transmembrane protein also known as Integrin Alpha X (ITGAX).,